Head-To-Head Comparison: Esperion Therapeutics (ESPR) & GenVec (GNVC)

Esperion Therapeutics (NASDAQ: ESPR) and GenVec (NASDAQ:GNVC) are both medical companies, but which is the better business? We will contrast the two companies based on the strength of their valuation, profitability, risk, analyst recommendations, dividends, earnings and institutional ownership.

Analyst Recommendations

This is a breakdown of recent ratings and recommmendations for Esperion Therapeutics and GenVec, as provided by MarketBeat.com.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Esperion Therapeutics 0 4 7 1 2.75
GenVec 0 2 0 0 2.00

Esperion Therapeutics presently has a consensus target price of $62.50, indicating a potential downside of 9.21%. GenVec has a consensus target price of $7.00, indicating a potential downside of 2.68%. Given GenVec’s higher possible upside, analysts clearly believe GenVec is more favorable than Esperion Therapeutics.

Insider & Institutional Ownership

92.2% of Esperion Therapeutics shares are owned by institutional investors. Comparatively, 6.2% of GenVec shares are owned by institutional investors. 32.5% of Esperion Therapeutics shares are owned by company insiders. Comparatively, 8.1% of GenVec shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth.


This table compares Esperion Therapeutics and GenVec’s net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Esperion Therapeutics N/A -74.10% -65.98%
GenVec -3,748.25% -648.22% -271.77%

Valuation and Earnings

This table compares Esperion Therapeutics and GenVec’s revenue, earnings per share (EPS) and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
Esperion Therapeutics N/A N/A -$74.97 million ($6.87) -10.02
GenVec N/A N/A N/A ($3.67) -1.96

Esperion Therapeutics is trading at a lower price-to-earnings ratio than GenVec, indicating that it is currently the more affordable of the two stocks.


Esperion Therapeutics beats GenVec on 8 of the 11 factors compared between the two stocks.

Esperion Therapeutics Company Profile

Esperion Therapeutics, Inc. is a lipid management company. The Company is a late-stage pharmaceutical company focused on developing and commercializing once-daily, oral therapies for the treatment of patients with elevated low-density lipoprotein cholesterol (LDL-C). With a targeted mechanism of action, bempedoic acid, the Company’s lead product candidate, is an orally available, once-daily adenosine triphosphate (ATP)-citrate lyase (ACL) inhibitor that reduces cholesterol biosynthesis and lowers elevated levels of LDL-C by up-regulating the LDL receptor, but with reduced potential for muscle-related side effects. In addition to bempedoic acid as monotherapy, the Company is also developing bempedoic acid in a fixed dose combination with ezetimibe, an approved, non-statin, oral, LDL-C lowering therapy. As of December 31, 2016, the Company was engaged in conducting its global Phase III clinical development program for bempedoic acid.

GenVec Company Profile

GenVec, Inc. (GenVec) is a clinical-stage biopharmaceutical company, engaged in the development of therapeutics and vaccines. The Company designs, tests and manufactures adenoviral-based product candidates. The Company’s development programs address therapeutic areas, such as hearing loss and balance disorders, as well as vaccines against infectious diseases, including respiratory syncytial virus (RSV), herpes simplex virus (HSV), Enterovirus D68 (EV-D68) and malaria. In the area of animal health, it is developing vaccines against foot-and-mouth disease (FMD). The Company develops and commercializes its product candidates through collaborations. The Company’s lead product candidate is CGF166. The Company’s vaccine candidates include preventative vaccines against RSV and malaria, and a therapeutic vaccine for HSV. The Company is developing vaccine and anti-viral candidates for the prevention and containment of FMD outbreaks.

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